While in the first period research of ETH Domain groups in Personalized Health had rather been oriented towards basic science, the aim of the second period was to fund projects with a close collaboration with hospitals. This was also facilitated thanks to the close and fruitful collaboration with the partner program “Swiss Personalized Health Network – SPHN”, and in particular by a number of commonly funded projects, notably, the four “National Data Streams – NDS”.
PHRT intends to take the last step toward clinical implementation with a focused yet compelling project in human research, i.e., a clinical trial, a clinical study or a research project according to the Swiss Human Research Act (HRA). PHRT, therefore, invites successful PHRT projects to apply for a respective project.
The ultimate goal of the PHRT program is to prove that the ETH Domain is able to take the last step of successful translational research by implementing and completing clinical studies / trials. That is why the PHRT Executive Committee (EC) decided to launch a special last call dedicated to the clinical implementation of concrete medical interventions / new technologies derived from particular promising projects and their consortia via a clinical study / trial defined as follows:
The preferred clinical study or trial aims at studying new tests, treatments or technologies and evaluates their effects or pertinence on human health outcomes. It can also be observational if the observation demonstrates in a scientifically sound and convincing manner the medical impact of the intervention / new technology.
In order to complete the clinical trial / study within the remaining funding period of PHRT, i.e., before December 31, 2025, a particular emphasis will be brought to the following selection criteria: composition of the consortium, proven performance, feasibility, project management / leadership, and likelihood of successful patient recruitment.
The clinical relevance of the research question and the openness for a collaboration with the ETH technology platforms digital Trial Intervention Platform (dTIP) and NEXUS Personalized Health will also be essential.
Submission of Expr of Interest: Jan 20, 2023
Invitation to submit full proposals: Feb 17, 2023
Submission of full proposals: March 31, 2023
Decision: end of May, 2023
Start of projects: June 2023