Call for Proposals:
Frequently asked questions (FAQs)
How to submit the PHRT proposal?
Compose one single PDF-file and send it to firstname.lastname@example.org
Where can I find regulations for research on humans, human embryonic stem cells or animals?
What is expected for the data management plan?
In case the proposal is funded, there will be in one way or another data generated. It is expected that applicants provide their anticipated planning concerning the data, which is for example:
what kind of data in generated, how much and at which frequency?
how are generated data processed, analyzed, forwarded, discussed, further exploited, distributed, shared, archived and retrieved?
what about data format and data standards?
who will be data owner, how are data protected, saved?
how will be responsible for the data, how long will these data have to be made available on which urgency level etc.
how will be a real but also a potential end user of data or further products (which ones)?
What to do if the proposal file is too large to be submitted by e-mail?
Please send an e-mail to email@example.com and attache a PDF with "Part 1 General Information".
Who is eligible as a main applicant (and hence, if approved, as a Principal Investigator, PI)?
The PI is the responsible researcher/clinician of the Pioneer Project. She/he needs, therefore, organizational, managerial and leadership skills to make the project a success in all respect. The PI can be employed at an institution of the ETH domain, a University, a hospital, etc. However, the consortium need at least one member that is employed at an ETH domain institution.
What do you mean by ‘homogeneous’ samples?
It means that all samples is expected to be taken in a equal/similar manner, that samples are handled, treated and stored in a same manner. Hence, it is rather a technologic homogeneity.
The call excludes FFPE samples. Would it be acceptable if the sample provider has established protocols for DNA and RNA extractions? Then we would not submit FFPE, but extracted DNA & RNA.
The reason why PHRT excluded FFPE samples is that there is no standardized method to extract DNA and RNA in a sufficient quality and homogeneity to do a matched WholeGenome-RNA and proteome sequencing (for protein sequencing, formalin do not cause problems).
The call excludes blood plasma samples. Can blood samples be sequences?
No, actually, blood as well as blood plasma samples are not suited to do a matched sequencing.